Introduction - Cordyceps and Mood
In recent years, there has been growing interest in natural remedies for enhancing mood and overall well-being. One such natural remedy that has gained attention is cordyceps, a type of medicinal mushroom with a rich history in traditional Chinese medicine.
Cordyceps is revered for its adaptogenic properties, and there is increasing evidence suggesting that it may have a positive impact on mood. In this article, we will delve into the potential benefits of cordyceps for mood enhancement and explore the scientific research supporting its use.
Cordyceps, scientifically known as Cordyceps sinensis, is a unique parasitic fungus that grows primarily in the high-altitude regions of Tibet, China, and Nepal. Traditionally, it has been used in Chinese medicine for centuries to promote vitality, longevity, and overall health.
Cordyceps is believed to exert its beneficial effects through a combination of bioactive compounds, including polysaccharides, nucleosides, and cordycepin.
The Link between Cordyceps and Mood
While much of the research on cordyceps has focused on its potential benefits for physical health, there is a growing body of evidence suggesting its positive impact on mental well-being, including mood regulation. Although the precise mechanisms of action are not yet fully understood, several studies have highlighted various ways in which cordyceps may influence mood.
Antioxidant and Anti-inflammatory Properties
Cordyceps contains powerful antioxidants that help combat oxidative stress and reduce inflammation in the body. Chronic inflammation and oxidative stress have been linked to mood disorders such as depression and anxiety.
By mitigating these factors, cordyceps may indirectly contribute to improved mood and overall mental well-being.
Studies have shown that cordyceps possesses neuroprotective properties, which can help protect brain cells from damage and promote neuronal growth.
This is particularly relevant to mood regulation, as disruptions in brain function and neurodegeneration have been implicated in mood disorders. By supporting brain health, cordyceps may help stabilize mood and enhance emotional resilience.
Regulation of Serotonin and Dopamine
Serotonin and dopamine are neurotransmitters that play crucial roles in regulating mood and emotions. Imbalances in these neurotransmitters have been associated with mood disorders.
Recent studies have demonstrated that cordyceps can modulate the levels of serotonin and dopamine in the brain, potentially contributing to improved mood and emotional well-being.
Cordyceps has been shown to aid in the production and balance of cortisol and other stress hormones, making it beneficial for adrenal health. Its adaptogenic qualities allow it to influence the body toward homeostatic balance, helping to stabilize stress hormone levels.
In a study conducted in 2003, Cordyceps extract was shown to improve physical performance in a group of rats during an endurance swim by over 16%. Additionally, the rats exhibited signs of reduced stress compared to the placebo group.
Another study in 2014 demonstrated that Cordyceps markedly reduced exercise-induced oxidative stress in rats. The study found that rats supplemented with Cordyceps had significantly increased production of intracellular antioxidants, such as superoxide dismutase, glutathione, and catalase, in their serum, liver, and muscle.
They also exhibited considerably lower levels of oxidative stress markers in these areas.
These findings suggest that Cordyceps can support adrenal health by helping the body manage stress, enhancing physical performance, and reducing oxidative stress.
By promoting homeostatic balance and supporting the adrenal glands' functions, Cordyceps may contribute to improved mood and overall well-being.
Researchers have postulated that Cordyceps may exert a positive effect on hormonal health by reducing the negative impacts of stress and enhancing sex hormone production.
In a study conducted in 1998, the potential benefits of Cordyceps on steroidogenesis, the process of producing steroid hormones, were investigated.
The study found that Cordyceps demonstrated a positive effect on steroidogenesis. This suggests that Cordyceps may have the ability to support the production of steroid hormones in the body.
Steroid hormones, such as testosterone, estrogen, and progesterone, play crucial roles in regulating various bodily functions, including reproductive health, mood and overall well-being.
We have all experienced how stress can exhaust our brain, and it is well-known that chronic stress can lead to chronic inflammatory states in the brain. These states of chronic inflammation have been observed in studies through the presence of various pro-inflammatory markers.
Furthermore, chronic stress is often associated with imbalances in neurotransmitter levels and reduced levels of brain-derived neurotrophic growth factors (BDNF).
Chronic stress has detrimental effects on memory, cognitive function, and emotional well-being. It impairs memory recall, cognitive processing speed, and reasoning skills.
Additionally, chronic stress contributes to the development of mood disorders and depression. It also accelerates the process of neurodegeneration, increasing the risk of diseases such as Parkinson's, dementia, and Alzheimer's.
When scientists study the deleterious effects of chronic stress on brain health, they focus on inflammatory markers like tumor necrosis factor alpha (TNF-a), interleukin-6, and NF-kb. They also investigate key neurotransmitters such as serotonin, norepinephrine, dopamine, acetylcholine, and gamma-aminobutyric acid (GABA), among others.
Studies show preliminary evidence that Cordyceps may have stress-reducing properties by reducing brain inflammation, increasing neurotrophic factors, and supporting antioxidant defense systems.
A study published in Evidence-Based Complementary and Alternative Medicine in 2014 examined the effects of Cordyceps supplementation on brain health.
The study demonstrated that Cordyceps reduced inflammatory markers in the hippocampus, a region of the brain associated with memory and learning.
Additionally, it increased brain-derived neurotrophic growth factor (BDNF) and 5-HTP levels, which are precursors to serotonin and norepinephrine. These results suggested that Cordyceps has positive benefits on mood and memory.
Another study conducted in 2012 investigated the effects of Cordyceps on brain inflammation in mice injected with D-galactose, a substance known to induce cognitive decline. The study found that Cordyceps supplementation lowered inflammatory markers in the brain and increased levels of key antioxidants such as superoxide dismutase and glutathione.
In contrast, the non-treated mice showed signs of early mental decline, while the Cordyceps-treated mice demonstrated improved cognitive function. Based on these findings, the researchers suggested that Cordyceps can enhance memory and ameliorate the decline of mental function.
More Scientific Studies on Cordyceps and Mood Enhancement
While much of the research on cordyceps' effects on mood is still in its early stages, several studies have shown promising results. For example, a randomized controlled trial published in the Journal of Alternative and
Complementary Medicine investigated the effects of cordyceps supplementation on individuals with major depressive disorder. The study found that cordyceps supplementation led to significant reductions in depressive symptoms compared to a placebo group.
Another study published in the Journal of Medicinal Food explored the effects of cordyceps extract on stress-induced behavioral changes in mice. The results indicated that cordyceps extract exhibited anxiolytic (anti-anxiety) and antidepressant effects, suggesting its potential as a natural mood enhancer.
Furthermore, a review article published in the Journal of Evidence-Based Complementary and Alternative Medicine analyzed multiple studies on cordyceps and mental health. The review concluded that cordyceps showed promise in improving mood, reducing anxiety, and enhancing overall well-being.
Dosage and Considerations
If you are considering using cordyceps to improve your mood, it is important to note that the optimal dosage may vary depending on individual
factors and the specific form of cordyceps being used. As with any supplement, it is recommended to consult with a healthcare professional before starting any new regimen.
Cordyceps is available in various forms. The dosage can range from 500 mg to 3,000 mg per day, depending on the product and individual needs. It is advisable to start with a lower dose and gradually increase it while monitoring how your body responds.
It's important to choose high-quality cordyceps products from reputable sources to ensure purity and potency. Look for products that have undergone third-party testing for quality and safety.
Other Lifestyle Factors for Mood Enhancement
While cordyceps shows promise as a natural mood enhancer, it is important to remember that maintaining good mental health involves a holistic approach. Alongside incorporating cordyceps into your routine, consider the following lifestyle factors to support your overall well-being:
Balanced Diet: A nutritious diet rich in fruits, vegetables, whole grains, and lean proteins provides essential nutrients for optimal brain function and mood regulation.
Regular Exercise: Physical activity releases endorphins, which are natural mood boosters. Engaging in regular exercise can help alleviate symptoms of depression and anxiety.
Adequate Sleep: Prioritize quality sleep as it plays a crucial role in maintaining emotional well-being. Aim for 7-9 hours of uninterrupted sleep each night.
Stress Management: Practice stress-reducing techniques such as mindfulness meditation, deep breathing exercises, or engaging in hobbies to promote relaxation and emotional balance.
Social Support: Cultivate meaningful connections with friends, family, or support groups to foster a sense of belonging and emotional support.
While more research is needed to fully understand the mechanisms by which cordyceps influences mood, the existing evidence suggests that it holds promise as a natural mood enhancer. Its antioxidant, anti-inflammatory, neuroprotective properties, and potential effects on serotonin and dopamine regulation make it an intriguing avenue for further exploration.
If you are interested in incorporating cordyceps into your routine, check out or award winning gummy, Mojo. Mojo gummies are the result of over a decade of research and development by our Chief Science Officer, Daniel Sanders.
Our team reverse-engineered a proprietary blend of functional mushrooms, herbs, adaptogens and roots that can increase energy and boost mood whilst combating brain fog and cognitive decline.
Table of contents